Comfortis PLUS

Comfortis PLUS Tablets for Dogs 40.1-60 lbs (18-27 kg) - Blue 6 Tablets

(You save $23.00)
( 3 Reviews )

Current stock: 36

Comfortis™ Plus (previously labelled Panoramis) kills fleas FAST* PLUS protects against intestinal worms and deadly heartworm

This is an Australian labelled pack (made in the United States) and due to a manufacturer restriction can't be shipped to the United States

  • Starts killing fleas in just 30 minutes
  • Prevents potentially fatal heartworm disease
  • Protects against intestinal parasites
  • Available in a convenient beef flavoured chewable tablet
  • Safe for puppies from 8 weeks of age

Comfortis™ Plus starts killing fleas in just 30 minutes, plus provides the added benefit of protection against deadly heartworm and intestinal worms. For immediate relief and month long protection Comfortis™ Plus is available in a convenient beef flavoured, chewable tablet.

Unlike spot on treatments there is no harmful reside that can rub or wash off, making Comfortis™ Plus the perfect choice for pet owners with young children or for dogs that are bathed regularly or enjoy a swim. Comfortis™ Plus is an ideal choice for:

  • Dog owners who dislike mess and inconvenience
  • Households with children or other pets
  • Dogs that swim or are washed frequently
  • Dogs with dermatological (skin) conditions requiring topical therapy


Important Safety Information

Comfortis™ Plus can be administered to puppies from 8 weeks of age. Puppies less than 14 weeks of age may experience an increased rate of vomiting. Seek veterinary advice regarding the use of Comfortis™ Plus in pregnant and lactating females, and in dogs with pre-existing epilepsy.

The safe use of Comfortis™ Plus in breeding males has not been evaluated.

Concurrent use of Comfortis™ Plus with high extra-label doses of ivermectin for parasitic mange or demodicosis may be associated with an increased risk of developing neurological signs typically associated with ivermectin toxicity. Comfortis™ Plus should not be administered concurrently with extra-label high doses of macrocyclic lactones.

The use of Comfortis™ Plus in dogs suffering from microfilaremia is not recommended. On rare occasions, transient shock-like (hypersensitivity) reactions have been observed in heartworm positive animals carrying a high number of microfilariae at the time of the first treatment with milbemycin oxime. Dogs with an existing adult D. immitis heartworm infection should be treated with an adulticide prior to commencement of Comfortis™ Plus.

The following adverse events have been recorded following administration of spinosad and milbemycin oxime together: vomiting, pruritis, lethargy and diarrhoea.

Active Ingredients

Comfortis™ Plus Chewable Tablets are available in variable strengths of spinosad + milbemycin oxime for oral administration to dogs.

Milbemycin oxime interferes with nerve transmission in invertebrates, which helps protect against heartworm, roundworm, hookworm and whipworm (minimum dose rate 0.5mg/kg).


Directions For Use

Comfortis™ Plus should be administered with food for maximum effectiveness. Comfortis™ Plus may be consumed as a treat by dogs when offered by the owner just prior to feeding. Alternatively, Comfortis™ Plus may be offered in food or administered like other tablet medications, in conjunction with a meal. To ensure that the entire dose is consumed, watch your dog for several minutes following tablet administration. If the entire dose is not consumed, re-dose as soon as possible with the full dose.

Comfortis™ Plus tablets are given orally, once a month at the recommended minimum dosage of 30 mg/kg body weight spinosad and 0.5 mg/kg milbemycin oxime.



1. Elanco study T9CUS100015, data on ¥ÌâÌ´åle.


* Spinosad starts to kill fleas in 30 minutes and is 100% effective in dogs within 4 hours - Elanco study T9C060330, data on file.1

3 Reviews

Greg 29th Mar 2020

Great Product

Love this product because it does three things in one pill. Been using it for years

Pat Pierce 2nd Feb 2018

Panoramis - Comforts Plus

Packaging/name has changed....dependability of the medicine remains wonderfully effective. I've used the milbemycin/spinosad combination for over a decade safely with multiple Australian Shepherds carrying or affected by the MDR1 mutation. As long as I remember to give meds on a full stomach, I've never once had a problem - and never had trouble with heart worms, fleas, or anything else. Great stuff!

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